Hormones 101, go DUTCH

This month I would like to bring the fabulous DUTCH test into focus. acronym for; Dry Urine Test For Comprehensive Hormones

If you think you have issues with chronic stress, that are affecting your hormones then this is the test for you to complete.  Like most private LAB tests it can be done in the privacy of your home, taking only minutes to complete.

MARKERS CONSIDERED IN THE DUTCH TEST

SAMPLE REPORT

Stress

The definition of STRESS is the down regulation of the HPA axis. Down-regulating the para-sympathetic nervous system, creating a dominant sympathetic response.

What happens when we get stressed? We release cortisol, taking 10 minutes to release, but then between 1-2 hour to break down.  This can vary however depending on the health of the individual, since the liver is involved within the process of breaking down cortisol when liver issues are present it can take 3-4 hours or even all day to break down.

Cortisol is then affected by the balance of all other hormones in your body. The Dutch test is a highly sensitive test, bringing all hormones into focus when considering your stress hormones.  See sample report above.

Cortisol is bound up by cortisol binding globulin transcortin.  Transcortin is very sensitive to estrogen.  Actually, all binding globulins are sensitive to estrogen.  Therefore, when a woman is on the contraceptive Pill, or has been on the Pill for some time, there is very good chance she is low in FREE cortisol, simply because it is all bound up to the binding globulins.

Free cortisol is less than 5% circulating, but in its active form.

SEX HORMONES

DHEA

DHEA, 80% is made in the adrenal glands 20% in the ovaries.

DHEAs is what is measured, however this is not the active form.  DHEA needs to un-S taking the S off to become the active form. This conversation is dependent on the SULT1A1 gene, therefore sulphonation plays a role.

DHEA is your master hormone, breaking down to the three estrogens.

If you’ve had your 23&Me interpreted, you can check to see the status of your SULT genes.

DHEA made in the brain protects the hippocampus from cortisol, therefore DHEA in the brain is a good thing.

Stress damages our hippocampus, affecting our short term memory, not good!


Cortisol

When we get too much free cortisol roaming the system, our receptor sensitivity stopping being so active. Adrenaline and cortisol end up circulating.  In this way chronic stress leads us into a rut, in which the wiring of our neural networks keeps us repeating the same dysfunctional behaviour.  Yet hoping for a different outcome! This by definition, is a form of insanity.


Adrenal Medulla

Other genes which are relevant to our stress response, mood and thinking are the COMT and MAOA. When these are running slow, you will not be breaking down catecholamines easily, and therefore do not break adrenaline down easily either. Check these genes if you are feeling stressed all day! Running slow means high amount of neurotransmitters are stored since you are not going to break down adrenaline or nora-adrenaline.  Rather, it can carry on ALL day.  Stressy, buzzy, tense.

All there needs to be present to impact this system significantly is infection, inflammation, food intolerance or a pile of house work building up to tip someone with slow genes to be tipped into over-whelm.

Cerebral cortex > CRH > anterior pituitary > ACTH > cortisol release > adrenaline and noradrenaline.

Our protective, survival mechanism is to shut down the parasympathetic nervous system and upregulate the sympathetic, now we are chronically in fight and flight! At this stage we are likely to get receptor sensitivity. We can liken this to ‘annoying kid syndrome’ which I use to called being ‘mummed’.  Mum, mum, mum .. for hours.  We then get hyper-sensitive, and cortisol goes up even further because we are not tolerating it.

On the other hand, if you are a super laid back person your COMT and/or MAOA may be running too quickly.  Feed the furnace with additional protein plus Tyrosine.


How do we break the cycle? 

Change the biochemistry through food and nutrient therapy and then also rewire your habits.

Two analogies work for me here:  First we need to dry up the riverbeds where ‘too much’ of a hormone / catecholamine / transmitter has been allowed to flood the system. Secondly, it takes a while for a worn-down path to grow grass again, where ‘not enough’ of the right hormone / catecholamine / transmitter has been present.


Stress and Fasting:

Clients like to bring in the option of fasting, believing that fasting will help to clear the system and take stress of the system.  Whilst this is true in cases where adrenal fatigue in NOT present, it is not true for those who do not have a robust HPA axis. Primarily cortisol manages blood sugar levels. Do not stress the system out even more by Fasting when adrenal dysregulation is present.


Auto-immunity

Cortisol is higher in the morning with the sun. When cortisol is high it supresses melatonin and growth hormone production.  Cortisol helps to fight infection via inflammation, think viruses, bacteria etc.  The pro-inflammatory cytokines stimulate the stress system releasing cortisol.

There is a real importance in this morning cortisol spike.  When auto-immune symptoms are presented then understanding your cortisol patterns is super important.  Low cortisol in the morning means that the auto-immune regulator does not happen.  Morning cortisol triggers those cells in the thymus who failed central tolerance to get destroyed.  What that means is, before immune cells get let out into the body, the thymus checks whether immune cells are auto-immune.  If cells are auto-immune, then the thymus pushes the cells off to the side and the thymes kill those cells.  Without the morning spike THIS DOES NOT HAPPEN!, and auto-immune cells get let out into the system.

Therefore, if we are consuming foods which create a cortisol spike at night, or we are fighting infection at night, this supresses melatonin, which in turn stops us from sleeping.  Leads to a low cortisol spike in the morning with auto-immune flare-ups.  For this reason gluten and HHV6 will play more than one roll in creating auto-immune flare-ups.


GET YOURSELF TESTED

When is it best time to test?

5-7 days after ovulation on days 19, 20, 21

If your cycles are long, then shift up. If your cycles are short, then shift down.

First, track your ovulation through temperature gauging or other symptoms.  Then count forward by 5-7 days and collect your urine.


Look at your Estrogens:

Dutch tests for Estrogens E1 E2 E3, which then go through the liver and get converted to Hydroxy 2, Hydroxy 4 or Hydroxy 16.

Each esterogen dominant pathway has key characteristics. Estrogen 4 hydroxy for instance goes down the quinone pathway, correcting to estrogen related cancers.

16 Hydroxy, the 2/16 ratio 2:16 can implicate estrogen proliferative symptoms such as moody, PMS, tender breasts and weight gain.

2 Hydroxy is the happy healthy way.

Estrogen in the right amount:

Good for > bone health

Good for > brain cognition

Good for > temperature regulation

Good for > collagen, tissue skin

Good for > fertility

When it’s decreased, we can face menopausal symptoms, skipping of cycles, low cholesterol even anorexia!

Too much estrogen, pre-disposed from either being on the contraceptive pill, environmental estrogens such as clingwrap, tap water (re-cycling of the hormone pill within the water system:

We can experience being over-weight, diabetes, increased risk of Alzheimer, PCOS.

Reduced hormones on the other hand can be as direct result from cholesterol reducing medication for instance. People seem to over-look that cholesterol makes up all our hormones.  When we lower cholesterol we also lower our testosterone, DHEA and Estrogens.


Other estrogen lowering activities:

Extreme exercise, marathon running, cross fit.

Frequent flying

Under appropriate boy weight.

Head injuries.

Surgery, decreases the blood flow to the area as capillaries are damaged.

Sugar, gums up the works, diabetes and smoking.

Birth control pill reduces estrogen in the long term.


Look at your Progesterone:

Progesterone helps with anxiety and insomnia as well as lining of the uterus, as women loosing progesterone report anxiety and insomnia.

Alpha-pregnanediol goes down, usually goes up to GABA, supporting the glymphatic system during sleep.

A-pregnanediol typically converts into neuro-steroid ALLO, that crosses BBB (blood brain barrier) and can activate GABA a-receptors.

Progesterone in the brain is calming, supporting neurons, and is even used after traumatic brain surgery or after Stroke.

Progesterone enhances serotonin receptors in the brain, and reduces gall bladder activity. Conversely, higher estrogen increases the risk of gall bladder disease and stones.

Those on lots of NSAIDS will typically have low progesterone activity when used for more than 10 days.


Look at your Androgens:

DHEA: facial hair, acne.


Look at your FREE cortisol, verses stored cortisol:

Consider infections

Consider allergies

Consider food intolerances

Consider weight gain


Marker 8-hydroxy-2-deoguanosine (8OHdG):

Marker correlating to chronic inflammation, high stress, high cortisol, insomnia, hypertension, kidney disease, IBD, depression.


What do we do with the information?

Note where on the dials we are, which is the dominant. Are we triple estrogen dominant?

Depending on where your markers are, we may wish to support Phase 1 liver with P450 enzymes and DIM. Or Phase 2 Liver with SamE precursor or SamE if you wish to order it in from the US.  P%P, Mg, Choline, Methionine, Methyl groups TMG are all useful here.

Foods can be influential, but ONLY if stomach acid is good.  This will not be the case where P5P and/or TMG is warranted. Kale, broccoli, Brussel Sprouts, Broccoli Sprouts, artichoke, onions, foods high in FOS and fiber.

Support Glymphatic system for catecholamine clearance at night.

Support MAOA with SamE donations and methyl donors.

Support COMT with Mg chloride.

Support serotonin pathway.

Support dopamine pathway.

Harness the benefits of apoptogenic herbs.

Combat infections.

Temper exercise according to the dominant hormone, verses hormone insufficiency.

Support HPA axis with key nutrients; C, B5, Zn, Fe, Mg, Sel

Weight management.

 

Given the results of your DUTCH test, there are plentiful options to improve your health 

If you are interested in ordering this test with result interpretation you can email Anna directly.

If you like this post, or found it interesting please do help to get our message out there and share it.  

Top 5 can-do’s to positively influence your health NOW!

5 Healthy Daily Habits

 

1.  Go to bed at 9pm

2.  Commit to NO BLUE LIGHT from computer screens or phones past sun-down. And when you do, wear amber glasses to block out the light.

3.  Have your last meal 3 hours before bedtime

4.  Break your fast more than 12 hours after your last meal, with a protein Break-Fast

5.  BREATH. Practice breathing OUT twice as long as you breath IN. This way you positively engage the parasympathetic nervous system. Allowing your body to heal naturally.


GO TO BED AT 9PM

ALTHOUGH ACTION-ING THIS IS NEAR IMPOSSIBLE WHEN YOU HAVE KIDS, IT’S WORTH KNOWING THAT OUR BODIES HAVE THEIR OWN AGENDA AND CONDITIONS WHEN IT COMES TO HEALTH.  IF YOU ARE NOT ACTUALLY GETTING TO BED BY 9PM, BE SURE YOU DON’T STAY UP IN FRONT OF YOUR COMPUTER.

WHICH BRINGS US TO THE SECOND POINT.


BLUE LIGHT & SLEEP

LIGHT FROM THE THE BLUE END OF THE SPECTRUM IS NATURAL AND COMES FROM SUNSHINE. HOWEVER, COMPUTER SCREENS, IPADS, FLAT-SCREENS, LED LIGHTING AND SMART PHONES ALSO ALL EMIT LARGE AMOUNTS OF BLUE LIGHT.  

RESEARCH HAS SHOWN THAT ALL LIGHT TOWARDS THE BLUE END OF THE SPECTRUM IS ESPECIALLY EFFECTIVE AT KEEPING YOU AWAKE BECAUSE IT SUPPRESSES THE PRODUCTION OF THE SLEEP-INDUCING HORMONE MELATONIN.

THEREFORE TIME SPENT WITH GADGETS BEFORE BEDTIME TRICKS THE PINEAL GLAND INTO STILL BELIEVING THAT IT IS STILL DAYTIME. 

IDEALLY, SWITCH GADGETS OFF AT LEAST 2 HOURS BEFORE BEDTIME.


PREPARE YOUR LAST MEAL EARLY, AND THEN EAT 3 HOURS PRIOR TO BED TIME AT THE LATEST. 

THIS GIVES YOUR BODY THE RECOMMENDED 12 HOURS FASTING PERIOD REQUIRED. 

DURING THE NIGHT TIME HOURS YOUR BODY SHOULD IDEALLY BE EMPTY ENOUGH TO CARRY OUT A SEMI DETOX DURING THE HOURS WHEN YOU SLEEP.  BETWEEN THE HOURS OF 1-3 AM OUR LIVER (THE GRAND-PARENT ORGAN) COMES INTO ACTION AND WORKS VERY HARD CLEANING-HOUSE! WHEN WE HAVE EATEN CLOSE TO BEDTIME, WE ARE UNABLE TO CLEANSE OUR BODIES ADEQUATELY, AND CAN EVEN WAKE THE FOLLOWING MORNING FEELING DRUNK AND SQUEEZY FROM THE FERMENTATION IN OUR GUTS. 


BREAK-FAST 12 HOURS AFTER YOUR LAST MEAL WITH A PROTEIN BREAKFAST.

AFTER 12 HOURS OUR BODIES WILL HAVE HAD THE TIME TO CLEANSE ADEQUATELY. THEN STARTING OUR DAY WITH A PROTEIN BREAKFAST PROVIDES THE BODY WITH THE BEST OPPORTUNITY TO STRENGTHEN THE LIVER AND AID LIVER PERFORMANCE. IT DOES NOT HAVE TO BE A LARGE BREAKFAST, EVEN NUT BUTTERS WITH PROTEIN POWDERS, BERRIES AND YOGHURT MAKE A GOOD, HIGH PROTEIN YET BALANCED BREAKFAST. 


BREATH 

BREATHING EXERCISES HAVE THE POWER TO RESTORE HEALTH ON THEIR OWN.

AT THE MORE EXTREME END OF THE SPECTRUM WE CAN TAKE ICE-MAN (FOR EXAMPLE), WHO HAS ACHIEVED BEYOND HUMAN POTENTIAL THOUGH BREATHING EXERCISES ALONE.

FOR US REGULAR FOLK, A REALLY GOOD BREATHING EXERCISE IS TO BREATH OUT TWICE AS LONG AS YOUR BREATH IN AND TO DO THIS FOR 7 MINUTES.  THIS ENGAGES THE PARASYMPATHETIC NERVOUS, WHILST SYSTEM REDUCING STRESS HORMONES AND SIGNALLING IN THE BODY PRESENT WHEN WE ARE SYMPATHETIC DOMINANT (FIGHT & FLIGHT) .

DIAPHRAGMATIC BREATHING ENGAGES THE DIAPHRAGM DURING THE BREATH.  YOU CAN PRACTICE DIAPHRAGMATIC BREATHING BY PLACING YOUR HAND ON THE STOMACH AREA, WHILST WATCHING THE STOMACH EXTEND AS THE BREATH IS DRAWN DOWN TO THE BASE YOUR LUNGS. WHEN YOU BREATH OUT, THE STOMACH GOES FLAT.

What is Chronic Fatigue? Part 2: Multiple systems under-functioning

Chronic Fatigue Syndrome is a notoriously tricky illness to pin-down.  Since CFS related health-issues tend to be serious to the degree that it can be life altering, but they are usually not so serious that they become a classified disease like heart disease.  This is not only confusing to the sufferer, but immensely frustrating too since many of the symptoms are not taken seriously by mainstream medicine.

1.  The first condition to be common among CFS sufferers is Adrenal Fatigue.

Unrecognised by most General Practitioners, Adrenal Fatigue affects our energy performance.  It influences how we regulate energy via our adrenal glands, but it is not Addison’s Disease – which is a recognised disease. Adrenal Fatigue is a serious life altering condition – but it is not adrenal failure.

So what tends to happen is the adrenal glands are tested with a blood test.  But because a blood test is not a sensitive enough test to pick up on adrenal dysregyulation, results come back suggesting they are functioning normally.

This presents false understanding and confusion when the sufferer is experiencing low energy due to sub-optimal adrenal function, but the tests being used are not sensitive enough to pick up on the true performance.

A four-point saliva test should be provided, obtainable by private labs through the UK and over-seas.  The four-point saliva test picks up on steroid hormone excretions throughout the day, tracking adaptogenic responses.  And therefore provides clear understanding of how the adrenal glands are ‘responding’ and adapting to daily stressors.


2.  The second condition is Left Ventricular Disease.

Studies release that a shocking 35% of us is said to have this condition, however the CFS / ME sufferer will experience the downstream effects of this condition as a chronic and debilitating element of the whole CFS picture.

They may be aware that their heart feels unstable, but unable to identify this through medical means since it is not classic heart disease and easily missed.


3.  The third piece to the Chronic Fatigue conundrum is the role of gut Dysbiosis.

Often present in those with Chronic Fatigue.  Gut Dysbiosis fits in to the picture of both Adrenal Fatigue and Chronic Fatigue Syndrome due to the role the adrenal glands play in providing an anti-inflammatory cortico-steroid (cortisol) to the body to buffer inflammation in the gut.

Causative factors for inflammation in the gut: 

Food Intolerances / Virus / Toxins such as methyl-mercury / Stress

Gut Dysbiosis has a number of potential causative factors with stress, food intolerances as well as toxins such as methyl mercury trumping possible causes for. Gut Dysbiosis is chronic low grade inflammation, however it is not inflammatory bowel disease (IBD) and therefore unrecognised by medical communities once again.


4.  The fourth mechanical issue to arise within CFS, and ties in with performance of the heart, liver and adrenal glands is Mitochondrial dysfunction.

This is not an inborn error of the mitochondria, however it is an inherited epigenetic malfunction.  What that means is that due to the environment the mitochondria has been presented within, functionality of mitochondria is reduced.  The trouble is, when there is poor mitochondrial function, then everything else in the body is affected.  But in particular the function of the heart and liver since this is where mot mitochondria resides.

Nutrients which positively support Mitochondria Function / Krebs Cycle:

D-Ribose / L-Carnitine / B3 (NAD) / Co-enzyme A / Co-enzyme Q10

What causes mitochondrial breakdown:

Crisps, rancid fats, hydrogenated oils, poor nutrient profile, toxic metals blocking biochemical pathways and oxidative stress.


5.  The fifth area of health which has more studies relating to CFS then any other area, is Nitric Oxide and Oxidative Stress.

Within the central nervous system and under normal conditions, Nitric Oxide (NO) is an important physiological signaling molecule, however when produced in large excess Nitric Oxide also displays neurotoxicity and is a risk to heart health.

Nitric Oxide has been found to be excessively high in Chronic Fatigue Sufferers and is seen in conjunction with risk factors for cardiovascular disease.


6.  The sixth element of Chronic Fatigue Syndrome is the observable Inflammation.

Inflammation is present but it is not a classifiable Auto-immune Disease.


7.  The seventh component to this complex condition is the presence of low grade infections.

Infections and co-infections are often present in CFS sufferers:

Ususal infections:

Epstein Bar / HHV6 / Enteroviruses / Cytomegalo viruses / Parovirus B19 / Retrovirus

Co-infections:

Mycoplasma / Chlamydia / Chronic Borrelia / Bucella / Rickettsia / Babesia 

Altogether we can view this complex condition as a disease of compromised milieu. Triggered by increased cellular stresses such as toxic heavy metals, infections and emotional stressors.

Strengthening the milieu / biological terrain interior will help to de-activate the viruses present.


8.  Finally the eighth piece in this Chronic Fatigue quandary, is emotional status of the CFS sufferer.

It is interesting to note that Chronic Fatigue patients tend to fall in three main personality categories known as energy depleting psychology types.

The Acheiver Perfectionis Type

Anxiety Type

The Helper Type

There can also be a genetic or epigenetic predisposition element to our stress responses to emotional trauma. Meaning that this can be either genetically inherited or genetically learned behaviour.  And then the condition / illness itself perpetuates further trauma in the sufferer as there is constant fear of becoming ill.  Other behaviours feed in to this cycle such as avoidance of certain foods and situations that they believe will make their condition worse.

Each category will be expanded upon within subsequent posts in the coming weeks.

 

 

 

 

 

 

What is Chronic Fatigue? Part 1: Definition and complex adaptive systems.

Chronic Fatigue, otherwise known as ME (Myalgic Encephalomyelitis), is a harrowing and debilitating condition, with no differential diagnosis in medical terms.  Diagnosis is exclusion based only, therefore other conditions similar by experience and presentation of symptoms, must first be eliminated. To receive the diagnosis of CFS/ME other possibilities such as cancer, liver disease, heart disease, auto immune condition must be eliminated.  When nothing else comes up after 6 months of unrelenting fatigue then the diagnosis is given.  This is the FUKUDA criteria.

Low grade chronic inflammation has been found consistently in those with Chronic Fatigue.  Inflammation of the brain and spinal chord as well as muscle pain and tenderness.  According to official guidelines in the realms of psychology 1990’s CFS was understood to be and unrelenting and debilitating condition, more functionally impaired that congestive heart failure, Multiple Sclerosis, Type 2 Diabetes, and even End stage renal disease!

 

The realms of psychology also cleverly defines CFS from depression by differentiating underlying motivations.

Ask the question ‘ What would you want to do with your life?’

The depressed person will tell you that they do not know.  While the CFS person will give you an in exhaustive list, but if it wasn’t for their energy!!

Do personality types then factor in to Chronic Fatigue Syndrome?

There is also a clinical definition of neuro chemistry which ties into psychological predisposition.  High serotonin is often found in those with Chronic Fatigue Syndrome rather than low serotonin.  Depression is LOW serotonin.

Chronic Fatigue has not gained much traction within medical communities, and this is largely down to the linear medical model and approach typically adopted by allopathic medicine.

Ultimately Chronic Fatigue Syndrome is a thresh-hold illness, with a range of imbalances resulting in a perfect storm ending up with post exertional fatigue and CFS.

This does not serve those with CFS/ME, since there are multiple biological adaptive systems which will be under-functioning.  And when you seek to support one system alone, within the Chronic Fatigue Model, you can very easily upset other systems which are also functioning to the brink of chaos and tip them over.

This is an extremely important point when understanding the nature of this condition and its healing pathway.  Since it feels as though we have lost control our bodies.  We are no longer in control of how much energy we have, there may be pain throughout the body and we seek to regain control.

And so, when multiple systems have collapsed and reorganised to a new level.  Meaning that the way we produce energy is no longer happening as it should, and we have limited energy, then this is the new norm, and the system is stable.  True, we don’t have energy, and we have lost control.  But, the system is still stable.

By attempting to heal CFS / ME without an understanding of how biological-systems lean in to each other.  Therefore looking at ‘communication between systems’, it becomes easy collapse currently stable systems into temporary chaos and to feel sicker than ever!

For this reason a wholistic approach, Otherwise known as a systems biology approach, which values multiple systems, is the only model which can successfully support the CFS sufferer toward health.  This is why the medical model cannot help the CFS / ME sufferer.  And we end up feeling sicker, more terrified, more out of control and more at sea with our symptoms than ever before.

 

 

Fatigue and Toxic Stress. 

What is Toxic Stress?

Toxic stress could be defined by the tipping-point between GOOD stress and BAD stress.

Stress can be experienced within the body as Thermal, Emotional, Electrical, Environmental and Physical.  Let’s face it, stress is commonality within 21st century day living, and perhaps a life without stress could almost appear dull!!

Some of us are stress addicts, though far from admitting it, we experience stress as a way of gaining traction.  As if the very meaning of having something to push up against creates the leverage required for profound advancements in daily and or work life.  The notion of being able to do plenty more when we have less time available, compared to dwindling hours away, unfocused when we somehow seemingly have time on our side.

Personally, I enjoy stress to some degree, or at least I did until my body (mainly my adrenal glands and mitochondria) realised that it had enough of it.

Partly because, as pointed out already, I have noticed that I get more done when a little stress is present in the back-drop of my mind and probably for the same reason I find it to focuses my mind more twenty-fold.

So when does healthy stress become toxic stress?  Or is all stress toxic?

From a nutritional and function medicine view-point, stress experienced in the body of an individual whose capacity to cope with stress has been compromised then ALL stress can be toxic.  This is true.

Within the body of the individual who has a healthy capacity to adapt to stress, then all stress may serve to strengthen.  In much the same way that a virus or bacteria in small doses strengthens the immune system, and even instigates growth in the development of a growing child.  Or the stress experienced by the beating of newly formed butterfly wings against the chrysalis

Research shows that Toxic stress is at the heart of our current dysfunctional energy regulation epidemic. And therefore the epidemic of complex health conditions and all auto-immune conditions prevalent today.

How many people do you know who are ‘tired all the time’? How many people do you know with an auto-immune condition?  Or a complex health condition with and unidentifiable cause.

Fatigue has become the common thread within complex, chronic and degenerative diseases

Why then do we not consider the biological mechanisms of energy production when considering complex chronic and degenerative diseases?  The fact is – modern medicine DOES NOT consider energy production pathways in this way.

Instead it concentrates on finding and naming the disease with a focus to creating a single drug as cure, rather than looking at the functional biology that cumulatively draws parallels within the disease condition and then supporting it.  Since naturally support of biological pathways would lead to greater health.

By contrast we are taught the simplistic theory that all of energy is derived from food and within that carbohydrate is the fundamental source.  I view this as likening human biology to little more than a car that consumes a single fuel.  The reality is that energy production is complex and involves more than one single biological system.

When considering energy production we could start by looking at synthesis of energy nutrients in the gut such as B-vitamins.  Equally the health of the gut is key in terms of capacity to receive, break down and transition nutrients through its fine intestinal walls for biological uptake. Nor lest do we consider the thyroid and it’s positioning as our metabolic gearbox, nor glycogenisis in the liver and the mobilisation of glycogen. Protein verses carbohydrate within the British food plate would have us convinced that carbohydrate is our sole source of energy. Energy = energy out.  As pointed out is likened to petrol in the car.

But we are not a car! Although the complexity of the human machine verses the model of the car (backed up by our British Food Plate theory) is a controversial topic.  The majority, who would prefer to consider low energy is due to a single issue, to be corrected via a single cure.

And then we have the adrenal glands, and the adaptive adrenal functions involving a squeeze of cortisol to mobilse sugar in to our blood during fight and flight.  But cortisol has multiple purposeful uses… the decreasing of inflammation in the gut due to post prandial stress or inflammation in the tissues, inflammation in the joints due to wear and tear from inappropriate exercise.  All this incrementally appropriates adaptive responses from the adrenal glands.  Cortisol, the potent anti-inflammatory hormone excreted from the adrenal glands is naturally in very high demand when high amounts of stress is experienced through inappropriate food intake, or otherwise.

‘A food intolerance’ it yet another villain to consider which again could enforce the illusion of a single culprit and single cure mentality.  And yes it is true again that the identification of food intolerances is key to biological health and can certainly make all the difference between no energy, foggy thinking and even a total loss of personality orientation OR clear thinking and vibrant health.  The dramatics of a food intolerance alone has left many a medic in both dis-belief and total denial around the very existence of this condition.

However like many other examples, a food intolerance is USUALLY only part of the complex whole.  And mainly due to the time delay between the damage food intolerances can cause and the identification of the food intolerance itself.

It is widely accepted that the longer one ignores an immunoglobin reaction in the gut the greater degree of inflammation and therefore damage to the gut lining.  What starts as a single food intolerance can easily perpetuate to chronic systemic inflammation, leaky gut and multiple food intolerances.  This intestinal bio-terrain is precursory to a range of complex heath conditions including auto-immune conditions.

These are some of the recommended test-kits when considering Energy production and Toxic stress

Chemical Immune Reactivity Screen

Lymphocyte Sensitivity Testing

Intestinal Antigenic Permeability Screen

Wheat/Gluten Proteome Reactivity & Autoimmunity

Gluten-Associated Cross-Reactive Foods and Foods Sensitivity

Adrenal Stress Profile

Metabolic Analysis Profile